Name | Magnesium potassium aspartate |
Synonyms | asparkam panangin tromcardin K-Mg Aspartate PotassiumMagnesiumAspartate magnesium potassium aspartate Magnesium potassium aspartate DL-Aspartate magnesium potassium l-aspartato(2-)-n,o(sup1))magnesate(2-) DL-Aspartic acid magnesium-potassium salt dl-aspartic acid magnesium-potassium salt dl-asparticacid,monopotassiumsalt,mixt.withpotassiumhydrogen(t-4)-bis(d |
CAS | 8076-65-1 |
InChI | InChI=1/3C4H7NO4.2K.Mg/c3*5-2(4(8)9)1-3(6)7;;;/h3*2H,1,5H2,(H,6,7)(H,8,9);;;/q;;;2*+1;+2/p-4 |
Molecular Formula | C8H11MgN2O8.C4H6NO4.2K |
Molar Mass | 497.78 |
Boling Point | 264.1°C at 760 mmHg |
Flash Point | 113.5°C |
Vapor Presure | 0.00289mmHg at 25°C |
Overview | the trade name of potassium magnesium aspartate (DL-potassiummagnesiumaspartate,DL) is panangin, also known as palazepam. DL-aspartic acid has the following important physiological functions: participate in the ornithine cycle, make NH3 and CO2 produce urea to achieve detoxification; Participate in the tricarboxylic acid cycle, promote energy metabolism, it is a catalyst for the synthesis and decomposition of high-energy phosphoric acid compounds; It participates in the generation of nucleotides and is an important substance for cell repair and regeneration; It can promote the excretion of bile and bile pigment, and has yellow discharge, reducing liver fat, increase liver glycogen and other effects; Promote the development and differentiation of T lymphocytes into mature T lymphocytes, have anti-viral and anti-tumor effects. Aspartic acid is a kind of amino acid with high affinity to cells, can be combined with metal ions (such as K, Mg2) into a strong complex. |
indications | this drug is an electrolyte supplement for the adjuvant treatment of the following diseases: acute and chronic hepatitis and cirrhosis, hepatic coma, drug-induced liver injury and other liver diseases. Various causes of adult and children arrhythmia, hypokalemia and Digitalis poisoning caused by arrhythmia, premature contraction, paroxysmal tachycardia, congestive heart failure, coronary heart disease, hypertension, myocardial damage caused by tumor chemotherapy and other cardiovascular diseases. Bronchial asthma, chronic obstructive pulmonary disease and chronic pulmonary heart disease and other respiratory diseases. Nervous system diseases, metabolic diseases. It can be used for pregnancy Vomit, pregnancy induced hypertension syndrome, low immune function, cardiac surgery, cardiopulmonary bypass, fatigue, hearing loss and so on. |
preparation | add 777.5gL-aspartic acid and 1.5L purified water into the reaction vessel, stir well until all are dissolved, then slowly add 358.7g potassium hydroxide solid (1.09eq) with stirring, exotherm, cool to room temperature and continue to stir until the system is dissolved, room temperature (20~25V) the pH of the solution was 7.5~8.0, and the L-aspartic acid potassium salt solution was obtained by fine filtration through a 0.45 μm pore size filter. Add 922.6gL-aspartic acid and 2L purified water into the reaction vessel, Heat to an internal temperature of 40 ℃, and stir well until all are dissolved, slowly add 165.8g light magnesium oxide solid (0.59eq) while stirring under heat preservation, exotherm, continue to stir until the system is dissolved, and cool to room temperature (20~25 ℃), the pH value of the detection solution was 7.5-8.0, and 3.3L of L-aspartic acid magnesium salt solution was obtained by fine filtration with a 0.45 μm pore size filter. Add the above L-aspartic acid potassium salt solution and the above L-aspartic acid magnesium salt solution into the reaction vessel, fully stir, room temperature (20~25 ℃) the pH value of the detection system was 7.0-8.0, and spray-dried to obtain 1.8 of L-aspartic acid potassium magnesium salt product. |